36-81
| Date | Series | Opponent | Result | CG Pitcher | Opp. Pitcher | Updated | |
|---|---|---|---|---|---|---|---|
| Apr 01 | 1 | @ Railroaders | W 2 - 1 | Cole (10-13) | Lynn (8-11) | 2021/03/24 - | |
| Apr 02 | 1 | @ Railroaders | W 2 - 1 | Eflin (0-16) | Keuchel (10-6) | 2021/03/24 - | |
| Apr 03 | 1 | @ Railroaders | W 2 - 1 | Urquidy (4-9) | Gonzales (12-6) | 2021/03/24 - | |
| Apr 04 | Off Day | ||||||
| Apr 05 | 2 | vs. Railroaders | L 1 - 2 | Musgrove (5-9) | Keller (10-11) | 2021/03/24 - | |
| Apr 06 | 2 | vs. Railroaders | L 1 - 2 | Cole (10-13) | Gausman (5-9) | 2021/03/24 - | |
| Apr 07 | 2 | vs. Railroaders | L 1 - 2 | Gomber (3-5) | Lynn (8-11) | 2021/03/24 - | |
| Apr 08 | 3 | vs. Titans | L 0 - 3 | Eflin (0-16) | Wainwright (8-1) | 2021/07/20 - | |
| Apr 09 | 3 | vs. Titans | L 0 - 3 | Urquidy (4-9) | Clevinger (7-2) | 2021/07/20 - | |
| Apr 10 | 3 | vs. Titans | L 0 - 3 | Musgrove (5-9) | Cody (4-6) | 2021/07/20 - | |
| Apr 11 | 4 | vs. Lancers | L 1 - 2 | Cole (10-13) | Minor (1-3) | 2021/03/13 - | |
| Apr 12 | 4 | vs. Lancers | L 1 - 2 | Gomber (3-5) | Bundy (6-10) | 2021/03/13 - | |
| Apr 13 | 4 | vs. Lancers | L 1 - 2 | Eflin (0-16) | Hendricks (9-11) | 2021/03/13 - | |
| Apr 14 | 5 | @ Titans | W 2 - 1 | Urquidy (4-9) | Clevinger (7-2) | 2021/07/20 - | |
| Apr 15 | 5 | @ Titans | W 2 - 1 | Musgrove (5-9) | Cody (4-6) | 2021/07/20 - | |
| Apr 16 | 5 | @ Titans | W 2 - 1 | Cole (10-13) | Walker (8-5) | 2021/07/20 - | |
| Apr 17 | Off Day | ||||||
| Apr 18 | 6 | @ Lancers | W 2 - 1 | Gomber (3-5) | Hendricks (9-11) | 2021/03/13 - | |
| Apr 19 | 6 | @ Lancers | W 2 - 1 | Eflin (0-16) | Bundy (6-10) | 2021/03/13 - | |
| Apr 20 | 6 | @ Lancers | W 2 - 1 | Cole (10-13) | Cobb (6-7) | 2021/03/13 - | |
| Apr 21 | 7 | @ Slaughter | L 1 - 2 | Urquidy (4-9) | McCullers (8-8) | 2021/04/27 - | |
| Apr 22 | 7 | @ Slaughter | L 1 - 2 | Musgrove (5-9) | Hudson (7-7) | 2021/04/27 - | |
| Apr 23 | 7 | @ Slaughter | L 1 - 2 | Gomber (3-5) | Giolito (8-5) | 2021/04/27 - | |
| Apr 24 | 8 | @ Knights | L 0 - 3 | Cole (10-13) | Woodruff (13-11) | 2021/04/13 - | |
| Apr 25 | 8 | @ Knights | L 0 - 3 | Eflin (0-16) | Carrasco (10-6) | 2021/04/13 - | |
| Apr 26 | 8 | @ Knights | L 0 - 3 | Urquidy (4-9) | Luzardo (9-7) | 2021/04/13 - | |
| Apr 27 | 9 | vs. Slaughter | L 1 - 2 | Musgrove (5-9) | Hudson (7-7) | 2021/04/27 - | |
| Apr 28 | 9 | vs. Slaughter | L 1 - 2 | Gomber (3-5) | Giolito (8-5) | 2021/04/27 - | |
| Apr 29 | 9 | vs. Slaughter | L 1 - 2 | Cole (10-13) | Glasnow (7-9) | 2021/04/27 - | |
| Apr 30 | 10 | vs. Knights | L 1 - 2 | Eflin (0-16) | Carrasco (10-6) | 2021/04/13 - | |
| May 01 | 10 | vs. Knights | L 1 - 2 | Musgrove (5-9) | Luzardo (9-7) | 2021/04/13 - | |
| May 02 | 10 | vs. Knights | L 1 - 2 | Urquidy (4-9) | Woodruff (13-11) | 2021/04/13 - | |
| May 03 | Off Day | ||||||
| May 04 | 11 | @ Warriors | W 2 - 1 | Cole (10-13) | Marquez (10-13) | 2021/05/31 - | |
| May 05 | 11 | @ Warriors | W 2 - 1 | Musgrove (5-9) | Nola (5-9) | 2021/05/31 - | |
| May 06 | 11 | @ Warriors | W 2 - 1 | Gomber (3-5) | Gallen (9-15) | 2021/05/31 - | |
| May 07 | 12 | vs. Warriors | L 1 - 2 | Eflin (0-16) | Anderson (5-6) | 2021/05/31 - | |
| May 08 | 12 | vs. Warriors | L 1 - 2 | Urquidy (4-9) | Marquez (10-13) | 2021/05/31 - | |
| May 09 | 12 | vs. Warriors | L 1 - 2 | Cole (10-13) | Nola (5-9) | 2021/05/31 - | |
| May 10 | 13 | vs. Stallions | L 1 - 2 | Musgrove (5-9) | Bassitt (5-12) | 2021/07/22 - | |
| May 11 | 13 | vs. Stallions | L 1 - 2 | Gomber (3-5) | Senzatela (7-8) | 2021/07/22 - | |
| May 12 | 13 | vs. Stallions | L 1 - 2 | Eflin (0-16) | Bauer (12-7) | 2021/07/22 - | |
| May 13 | Off Day | ||||||
| May 14 | 14 | vs. Thunder | L 1 - 2 | Cole (10-13) | Plesac (8-6) | 2021/06/24 - | |
| May 15 | 14 | vs. Thunder | L 1 - 2 | Urquidy (4-9) | DeGrom (4-8) | 2021/06/24 - | |
| May 16 | 14 | vs. Thunder | L 1 - 2 | Musgrove (5-9) | Berrios (4-9) | 2021/06/24 - | |
| May 17 | 15 | @ Stallions | L 0 - 3 | Eflin (0-16) | Bauer (12-7) | 2021/07/22 - | |
| May 18 | 15 | @ Stallions | L 0 - 3 | Urquidy (4-9) | Kelly (5-7) | 2021/07/22 - | |
| May 19 | 15 | @ Stallions | L 0 - 3 | Cole (10-13) | Davies (12-10) | 2021/07/22 - | |
| May 20 | 16 | @ Thunder | W 2 - 1 | Musgrove (5-9) | DeGrom (4-8) | 2021/06/24 - | |
| May 21 | 16 | @ Thunder | W 2 - 1 | Gomber (3-5) | Berrios (4-9) | 2021/06/24 - | |
| May 22 | 16 | @ Thunder | W 2 - 1 | Eflin (0-16) | Fried (5-8) | 2021/06/24 - | |
| May 23 | Off Day | ||||||
| May 24 | 17 | @ Broncos | W 2 - 1 | Cole (10-13) | Castano (4-3) | 2021/06/08 - | |
| May 25 | 17 | @ Broncos | W 2 - 1 | Urquidy (4-9) | Happ (3-11) | 2021/06/08 - | |
| May 26 | 17 | @ Broncos | W 2 - 1 | Gomber (3-5) | Means (4-9) | 2021/06/08 - | |
| May 27 | 18 | vs. Broncos | W 2 - 1 | Musgrove (5-9) | Peterson (3-5) | 2021/06/08 - | |
| May 28 | 18 | vs. Broncos | W 2 - 1 | Cole (10-13) | Gray (1-4) | 2021/06/08 - | |
| May 29 | 18 | vs. Broncos | W 2 - 1 | Eflin (0-16) | Castano (4-3) | 2021/06/08 - | |
| May 30 | 19 | vs. Turtles | L 0 - 3 | Urquidy (4-9) | Ryu (13-3) | 2021/08/10 - | |
| May 31 | 19 | vs. Turtles | L 0 - 3 | Gomber (3-5) | Brault (1-2) | 2021/08/10 - | |
| Jun 01 | 19 | vs. Turtles | L 0 - 3 | Cole (10-13) | Wheeler (11-4) | 2021/08/10 - | |
| Jun 02 | 20 | vs. Hounds | L 0 - 3 | Eovaldi (2-5) | Kim (5-2) | 2021/08/19 - | |
| Jun 03 | 20 | vs. Hounds | L 0 - 3 | Eflin (0-16) | Lamet (4-10) | 2021/08/19 - | |
| Jun 04 | 20 | vs. Hounds | L 0 - 3 | Cease (1-1) | Gray (9-8) | 2021/08/19 - | |
| Jun 05 | Off Day | ||||||
| Jun 06 | 21 | @ Turtles | L 1 - 2 | Cole (10-13) | Wheeler (11-4) | 2021/08/10 - | |
| Jun 07 | 21 | @ Turtles | L 1 - 2 | Gomber (3-5) | Darvish (16-3) | 2021/08/10 - | |
| Jun 08 | 21 | @ Turtles | L 1 - 2 | Musgrove (5-9) | Maeda (16-2) | 2021/08/10 - | |
| Jun 09 | 22 | @ Hounds | L 1 - 2 | Eflin (0-16) | Gray (9-8) | 2021/08/19 - | |
| Jun 10 | 22 | @ Hounds | L 1 - 2 | Cease (1-1) | Kim (5-2) | 2021/08/19 - | |
| Jun 11 | 22 | @ Hounds | L 1 - 2 | Cole (10-13) | Castillo (4-3) | 2021/08/19 - | |
| Jun 12 | 23 | @ Railroaders | L 0 - 3 | Gomber (3-5) | Keuchel (10-6) | 2021/03/14 - | |
| Jun 13 | 23 | @ Railroaders | L 0 - 3 | Musgrove (5-9) | Gausman (5-9) | 2021/03/14 - | |
| Jun 14 | 23 | @ Railroaders | L 0 - 3 | Eflin (0-16) | Keller (10-11) | 2021/03/14 - | |
| Jun 15 | Off Day | ||||||
| Jun 16 | 24 | @ Titans | L 1 - 2 | Cole (10-13) | Walker (8-5) | 2021/08/10 - | |
| Jun 17 | 24 | @ Titans | L 1 - 2 | Urquidy (4-9) | Kershaw (7-7) | 2021/08/10 - | |
| Jun 18 | 24 | @ Titans | L 1 - 2 | Gomber (3-5) | Wainwright (8-1) | 2021/08/10 - | |
| Jun 19 | Off Day | ||||||
| Jun 20 | 25 | @ Lancers | L 1 - 2 | Musgrove (5-9) | Turnbull (6-7) | 2021/06/15 - | |
| Jun 21 | 25 | @ Lancers | L 1 - 2 | Cole (10-13) | Bundy (6-10) | 2021/06/15 - | |
| Jun 22 | 25 | @ Lancers | L 1 - 2 | Eflin (0-16) | Cobb (6-7) | 2021/06/15 - | |
| Jun 23 | 26 | vs. Slaughter | L 0 - 3 | Urquidy (4-9) | Giolito (8-5) | 2021/07/08 - | |
| Jun 24 | 26 | vs. Slaughter | L 0 - 3 | Gomber (3-5) | Glasnow (7-9) | 2021/07/08 - | |
| Jun 25 | 26 | vs. Slaughter | L 0 - 3 | Musgrove (5-9) | Urias (8-6) | 2021/07/08 - | |
| Jun 26 | 27 | vs. Knights | L 1 - 2 | Cole (10-13) | Alcantara (11-5) | 2021/05/20 - | |
| Jun 27 | 27 | vs. Knights | L 1 - 2 | Eflin (0-16) | Carrasco (10-6) | 2021/05/20 - | |
| Jun 28 | 27 | vs. Knights | L 1 - 2 | Urquidy (4-9) | Woodruff (13-11) | 2021/05/20 - | |
| Jun 29 | Off Day | ||||||
| Jun 30 | All-Star Game | ||||||
| Jul 01 | Off Day | ||||||
| Jul 02 | 28 | vs. Railroaders | L 0 - 3 | Cole (10-13) | Gonzales (12-6) | 2021/08/27 - | |
| Jul 03 | 28 | vs. Railroaders | L 0 - 3 | Eovaldi (2-5) | Keller (10-11) | 2021/08/27 - | |
| Jul 04 | 28 | vs. Railroaders | L 0 - 3 | Eflin (0-16) | Gausman (5-9) | 2021/08/27 - | |
| Jul 05 | 29 | vs. Titans | L 0 - 3 | Musgrove (5-9) | Walker (8-5) | 2021/08/27 - | |
| Jul 06 | 29 | vs. Titans | L 0 - 3 | Hernandez (2-0) | Cahill (0-0) | 2021/08/27 - | |
| Jul 07 | 29 | vs. Titans | L 0 - 3 | Cole (10-13) | Wainwright (8-1) | 2021/08/27 - | |
| Jul 08 | 30 | vs. Lancers | L 1 - 2 | Eovaldi (2-5) | Bundy (6-10) | 2021/08/31 - | |
| Jul 09 | 30 | vs. Lancers | L 1 - 2 | Eflin (0-16) | Turnbull (6-7) | 2021/08/31 - | |
| Jul 10 | 30 | vs. Lancers | L 1 - 2 | Musgrove (5-9) | Minor (1-3) | 2021/08/31 - | |
| Jul 11 | 31 | @ Slaughter | L 0 - 3 | Hernandez (2-0) | Hudson (7-7) | 2021/09/14 - | |
| Jul 12 | 31 | @ Slaughter | L 0 - 3 | Cole (10-13) | Giolito (8-5) | 2021/09/14 - | |
| Jul 13 | 31 | @ Slaughter | L 0 - 3 | Eovaldi (2-5) | Glasnow (7-9) | 2021/09/14 - | |
| Jul 14 | Off Day | ||||||
| Jul 15 | 32 | @ Knights | L 1 - 2 | Eflin (0-16) | Snell (9-11) | 2021/08/27 - | |
| Jul 16 | 32 | @ Knights | L 1 - 2 | Musgrove (5-9) | Carrasco (10-6) | 2021/08/27 - | |
| Jul 17 | 32 | @ Knights | L 1 - 2 | Hernandez (2-0) | Woodruff (13-11) | 2021/08/27 - | |
| Jul 18 | 33 | @ Thunder | L 1 - 2 | Cole (10-13) | Berrios (4-9) | 2021/09/14 - | |
| Jul 19 | 33 | @ Thunder | L 1 - 2 | Eovaldi (2-5) | DeGrom (4-8) | 2021/09/14 - | |
| Jul 20 | 33 | @ Thunder | L 1 - 2 | Eflin (0-16) | Lopez (7-6) | 2021/09/14 - | |
| Jul 21 | 34 | @ Broncos | Urquidy (4-9) | Corbin (0-1) | - | ||
| Jul 22 | 34 | @ Broncos | Gomber (3-5) | Peterson (3-5) | - | ||
| Jul 23 | 34 | @ Broncos | Cole (10-13) | Happ (3-11) | - | ||
| Jul 24 | Off Day | ||||||
| Jul 25 | 35 | vs. Thunder | Eovaldi (2-5) | DeGrom (4-8) | - | ||
| Jul 26 | 35 | vs. Thunder | Eflin (0-16) | Lopez (7-6) | - | ||
| Jul 27 | 35 | vs. Thunder | Urquidy (4-9) | Plesac (8-6) | - | ||
| Jul 28 | 36 | vs. Broncos | Gomber (3-5) | Gray (1-4) | - | ||
| Jul 29 | 36 | vs. Broncos | Cole (10-13) | Castano (4-3) | - | ||
| Jul 30 | 36 | vs. Broncos | Eovaldi (2-5) | Mize (1-1) | - | ||
| Jul 31 | 37 | vs. Turtles | L 1 - 2 | Urquidy (4-9) | Ryu (13-3) | 2021/08/29 - | |
| Aug 01 | 37 | vs. Turtles | L 1 - 2 | Musgrove (5-9) | Wheeler (11-4) | 2021/08/29 - | |
| Aug 02 | 37 | vs. Turtles | L 1 - 2 | Cole (10-13) | Maeda (16-2) | 2021/08/29 - | |
| Aug 03 | 38 | vs. Hounds | Eovaldi (2-5) | Gray (9-8) | - | ||
| Aug 04 | 38 | vs. Hounds | Eflin (0-16) | Bieber (18-4) | - | ||
| Aug 05 | 38 | vs. Hounds | Musgrove (5-9) | Castillo (4-3) | - | ||
| Aug 06 | 39 | @ Turtles | Hernandez (2-0) | Wheeler (11-4) | - | ||
| Aug 07 | 39 | @ Turtles | Cole (10-13) | Maeda (16-2) | - | ||
| Aug 08 | 39 | @ Turtles | Eovaldi (2-5) | Darvish (16-3) | - | ||
| Aug 09 | Off Day | ||||||
| Aug 10 | 40 | @ Hounds | Eflin (0-16) | Gray (9-8) | - | ||
| Aug 11 | 40 | @ Hounds | Musgrove (5-9) | Lamet (4-10) | - | ||
| Aug 12 | 40 | @ Hounds | Cease (1-1) | Burnes (7-4) | - | ||
| Aug 13 | 41 | @ Warriors | L 0 - 3 | Cole (10-13) | Young (1-4) | 2021/08/29 - | |
| Aug 14 | 41 | @ Warriors | L 0 - 3 | Eovaldi (2-5) | Skubal (1-2) | 2021/08/29 - | |
| Aug 15 | 41 | @ Warriors | L 0 - 3 | Eflin (0-16) | Gallen (9-15) | 2021/08/29 - | |
| Aug 16 | 42 | @ Stallions | Musgrove (5-9) | Bassitt (5-12) | - | ||
| Aug 17 | 42 | @ Stallions | Hernandez (2-0) | Bauer (12-7) | - | ||
| Aug 18 | 42 | @ Stallions | Cole (10-13) | Senzatela (7-8) | - | ||
| Aug 19 | 43 | vs. Warriors | L 1 - 2 | Eovaldi (2-5) | Young (1-4) | 2021/08/29 - | |
| Aug 20 | 43 | vs. Warriors | L 1 - 2 | Eflin (0-16) | Gallen (9-15) | 2021/08/29 - | |
| Aug 21 | 43 | vs. Warriors | L 1 - 2 | Cease (1-1) | Skubal (1-2) | 2021/08/29 - | |
| Aug 22 | 44 | vs. Stallions | Hernandez (2-0) | Bauer (12-7) | - | ||
| Aug 23 | 44 | vs. Stallions | Cole (10-13) | Senzatela (7-8) | - | ||
| Aug 24 | 44 | vs. Stallions | Eovaldi (2-5) | Kelly (5-7) | - | ||
| Aug 25 | Off Day | ||||||
| Aug 26 | 45 | @ Titans | Eflin (0-16) | Cobb (6-7) | - | ||
| Aug 27 | 45 | @ Titans | Musgrove (5-9) | Walker (8-5) | - | ||
| Aug 28 | 45 | @ Titans | Hernandez (2-0) | Cahill (0-0) | - | ||
| Aug 29 | 46 | @ Lancers | W 2 - 1 | Cease (1-1) | Dunning (3-3) | 2021/08/31 - | |
| Aug 30 | 46 | @ Lancers | W 2 - 1 | Eovaldi (2-5) | Soroka (2-2) | 2021/08/31 - | |
| Aug 31 | 46 | @ Lancers | W 2 - 1 | Eflin (0-16) | Bundy (6-10) | 2021/08/31 - | |
| Sep 01 | Off Day | ||||||
| Sep 02 | 47 | vs. Titans | Musgrove (5-9) | Walker (8-5) | - | ||
| Sep 03 | 47 | vs. Titans | Hernandez (2-0) | Cahill (0-0) | - | ||
| Sep 04 | 47 | vs. Titans | Cole (10-13) | Wainwright (8-1) | - | ||
| Sep 05 | 48 | vs. Lancers | Eovaldi (2-5) | Bundy (6-10) | - | ||
| Sep 06 | 48 | vs. Lancers | Eflin (0-16) | Minor (1-3) | - | ||
| Sep 07 | 48 | vs. Lancers | Cease (1-1) | Turnbull (6-7) | - | ||
| Sep 08 | 49 | vs. Slaughter | Hernandez (2-0) | McCullers (8-8) | - | ||
| Sep 09 | 49 | vs. Slaughter | Cole (10-13) | Singer (0-1) | - | ||
| Sep 10 | 49 | vs. Slaughter | Eovaldi (2-5) | Giolito (8-5) | - | ||
| Sep 11 | Off Day | ||||||
| Sep 12 | 50 | @ Slaughter | Eflin (0-16) | Glasnow (7-9) | - | ||
| Sep 13 | 50 | @ Slaughter | Gomber (3-5) | Urias (8-6) | - | ||
| Sep 14 | 50 | @ Slaughter | Hernandez (2-0) | McCullers (8-8) | - | ||
| Sep 15 | 51 | @ Knights | Cole (10-13) | Garcia (3-1) | - | ||
| Sep 16 | 51 | @ Knights | Eovaldi (2-5) | Carrasco (10-6) | - | ||
| Sep 17 | 51 | @ Knights | Eflin (0-16) | Luzardo (9-7) | - | ||
| Sep 18 | 52 | vs. Knights | Gomber (3-5) | Howard (1-1) | - | ||
| Sep 19 | 52 | vs. Knights | Hernandez (2-0) | Woodruff (13-11) | - | ||
| Sep 20 | 52 | vs. Knights | Cole (10-13) | Garcia (3-1) | - | ||
| Sep 21 | Off Day | ||||||
| Sep 22 | 53 | vs. Railroaders | L 0 - 3 | Eovaldi (2-5) | Lynn (8-11) | 2021/08/27 - | |
| Sep 23 | 53 | vs. Railroaders | L 0 - 3 | Eflin (0-16) | Gausman (5-9) | 2021/08/27 - | |
| Sep 24 | 53 | vs. Railroaders | L 0 - 3 | Cease (1-1) | Gonzales (12-6) | 2021/08/27 - | |
| Sep 25 | 54 | @ Railroaders | W 2 - 1 | Hernandez (2-0) | Keuchel (10-6) | 2021/08/27 - | |
| Sep 26 | 54 | @ Railroaders | W 2 - 1 | Cole (10-13) | Keller (10-11) | 2021/08/27 - | |
| Sep 27 | 54 | @ Railroaders | W 2 - 1 | Eovaldi (2-5) | Lynn (8-11) | 2021/08/27 - |